Pustaka Ilmiah Universitas Padjadjaran

Abstrak

Effect of Curcuma xanthorrhiza Roxb. Decoct on Glucose Absorption Level in Intestine of Male Rat of Wistar Strain

Almost of Indonesian Jamu consist of Curcuma xanthorrhiza Roxb., it contains curcuminoid which has effect in increasing the absorption of glucose on intestine of rat. Therefore the diabetic patient or the peoples who have problem with their blood glucose have to be careful for drink it. To answer the worried about this effect, the effect of the minimal dose of this traditional medicine has been observed.

The effect of decoct was measured at the dose 160 mg/kg BW of rat in the 100 ml of mixture 30 mM glucose in 0,9 % sodium chloride solution. Rat was anaesthetic by urethane. The mixture of 30 mM glucose in 0,9 % sodium chloride solution as a control solution, then decoct, through in intestine for one hour, respectively. Every 15 minutes the glucose solution concentration was measured. The decrease of glucose solution concentration is similar to the absorption level of glucose solution by intestine.

The levels of glucose absorption of control and decoct were 76.98 % and 73,57 %, respectively

In conclusion, the decoct of Curcuma xanthorrhiza Roxb. at 160 mg/kg BW of rat has effect to decrease the glucose absorption level on intestine, although is not significant.