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Antiplasmodial and other constituents from four Indonesian Garcinia spp.

Antiplasmodial and other constituents from four Indonesian Garcinia spp.
Elfita Elfita, Muharni Muharni, Madyawati Latief, Darwati Darwati, Ari Widiyantoro, Supriyatna Supriyatna, Husein H. Bahti, Dachriyanus Dachriyanus, Paul Cos, Louis Maes, Kenne Foubert, Sandra Apers, Luc Pieters
Universitas Padjadjaran,Phytochemistry 70 (2009)907-912, Contents lists available at ScienceDirect, journal homepage: www.elsevier.com/locate/phytochem, doi:10.1016/phytochem.2009.04.024
Bahasa Inggris
Universitas Padjadjaran,Phytochemistry 70 (2009)907-912, Contents lists available at ScienceDirect, journal homepage: www.elsevier.com/locate/phytochem, doi:10.1016/phytochem.2009.04.024
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Phytochcmical investigations of four Garcinia spp, from Indonesia. i.e. Garcinia griffithii T. Anderson. Garcinia celebica L, Garcinia cornea L.. and Garcinia cymosa K. Schum (Clusiacea) have resulted in the isolation of a xanthone, 1,5-dihydroxy-3,6-dimethoxy-2.7-diprenyixarithone. 1.7-dihydroxyxanthone. isoxanth¬ochymol. β-sitosterol-3-0- β -o-glucoside and stigmasterol-3-0-β-o-gIucoside from the stem bark of G. Griffithii; friedelin and 3 β -hydroxy-23-oxo-9.16-lanostadien-26-oic acid or garcihombronane D from leaves of G. celebica: 23-hydroxy-3-oxo-cycloart-24-en-26-oic acid and epicatechin from stem bark of G. cornea: (+)-morelloflavone. morelloflavone-7-0-β-D-glucoside or fukugiside. the triterpene 3 β hydroxy-5-glutinen-28-oic acid and canophyllol From stem bark of G. cymosa. The xanthone and garci¬hombronane D displayed a selective activity against Plasmadion falciparum: isoxanthochymol and the triterpene β-hydroxy-5-glutinen-28-oic acid a broad but non-selective antiprotozual activity.

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