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Anti-bacterial Activity of Prenylated Xanthone from The Bark of Garcinia lowa

Anti-bacterial Activity of Prenylated Xanthone from The Bark of Garcinia lowa
Darwati, Elisabeth Krismayanti, Supriyatna, Unang Supratman
Universitas Padjadjaran, Jurnal Kimia VALENSI: Jurnal Penelitian dan Pengembangan Ilmu Kimia, 2(2), November 2016, 81-84, P-ISSN:2460-6065, E-ISSN: 2548-3013
Bahasa Inggris
Universitas Padjadjaran, Jurnal Kimia VALENSI: Jurnal Penelitian dan Pengembangan Ilmu Kimia, 2(2), November 2016, 81-84, P-ISSN:2460-6065, E-ISSN: 2548-3013
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Bioactivity-guided fractionation of a ethyl acetate extract of Garcinia Iowa bark has led to the isolation and identification of a known prenylated xanthone, mangosharin, (2,6-dihydroxy-8-methoxy-5-(3-methylbut-2-enyI)- xanthone (1, 15.4 mg) The structure of the compound was identified from analysis of their spectroscopic data and by comparison with previous studies.Compound 1 showed anti-bacterial activity against Sreptococcus mutans with MIC value of 7.25 μg/mL.

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