Abstrak RSS

Insecticidal Compounds from Indonesian Plants

Insecticidal Compounds from Indonesian Plants
Unang Supratman, Tri Mayanti, Tali Herlina,Euis Julaeha, Nurlelasari, Desi Harneti, Hideo Hayashi
Universitas Padjadjaran, Prosiding Seminar Kimia Bersama ITB-UKM Keenam "Perkembangan Terkini Ilmu Kimia Yang Berlandaskan Kajian Sumber Alam", Denpasar, 17-18 Mei 2005 Bali-Indonesia, ISBN: 979-9299-16-0, Homepage : https://www.chem.itb.ac.id/jschem
Bahasa Inggris
Universitas Padjadjaran, Prosiding Seminar Kimia Bersama ITB-UKM Keenam "Perkembangan Terkini Ilmu Kimia Yang Berlandaskan Kajian Sumber Alam", Denpasar, 17-18 Mei 2005 Bali-Indonesia, ISBN: 979-9299-16-0, Homepage : https://www.chem.itb.ac.id/jschem
, , , ,

During the random screening of Indonesian plants for insecticidal compounds. Kalanchoe pinnata and K. daigrernontiana were found to show a potent insecticidal activity against the third larvae of silkworm (Bombyx mori). K. pinnata leaves were shown to produce a new insecticidal bufadienolide. bryophyllin C and a known bufadienolide. bryopltyllin A. together with an inactive bersaldegenin-3-acetate. meanwhile a new insecticidal bufadienolide. methyl daigremonate and three known bufadienolides. bersaldegenin-l,3,5-orthoacetate. daigremontianin. and bersaldegenin-l-acetate were isolated from the leaves of K. daigremontiana In order to clarify the functional groups responsible for the insecticidal activity. two a-pyrone opening derivatives were prepared and their insecticidal activity was compared with those of other bufadienolides. As a result, both the orthoacetate and a-pyrone moiety seemed to be essential structural elements for exhibiting a potent insecticidal activity. In addition, oxygenated substituents at C-11 and C-12 in ring C enhanced the insecticidal activity.

Download: .Full Papers