Pustaka Ilmiah Universitas Padjadjaran

Abstrak

Comparative Antihelmintic Activities Of Morinda Citrifolia L. And Leucaena Leucocephala Lam. Infuses

Sixty percent of Indonesian people were estimated of worm infected. Morinda citrifolia and Leucaena leucocephala are traditional medicine for helminthiases. Morinda citrifolia is a popular fruit and was used for more indications, it has an expensive price. On the contrary Leucaena leucocephala has cheap price. Base on the differences, we researched the antihelmintic activities to Ascaris suum. The antihelmintic activities were conducted using experimental in vitro technique. Control (NaCL 0.9% solution), reference (mebendazole) and test compound were tested by 10 worms. Parameters are the amount of dead worms in 24 hours and the onset of action. Onset of action is calculated by the time needed to kill all Ascaris suum. The results were statistically analyzed. Morinda citrifolia fruit infusion has best antihelmintic activity at the concentrations 30%, onset of action at 30% is 11 hours.Leucaena leucocephala infuse has best antihelmintic activity at the concentrations 30%, onset of action at 30% is 15 hours. In conclusion the strongest antihelmintic activity was infuses of Morinda citrifolia followed Leucaena leucocephala.