Abstrak 
Flavonoid Compound From the Stem bark of Drimys beccariana and its Antiplasmodial Activity against Plasmodium falciparum
Tarso Rudiana, Euis Julaeha, Tati Herlina
Unpad
Bahasa Indonesia, Bahasa Inggris
Unpad
antiplasmodial, antiplasmodium, D. beccariana, P. falciparum, pilloin, piloin
Senyawa piloin (5,3′-dihidroksi-7,4′-dimetoksi flavon) telah diisolasi dari kulit batang tanaman D. beccariana. Struktur kimia piloin diidentifikasi berdasarkan data spektroskopi, meliputi UV, IR, NMR (1H, 13C, DEPT 135°, HMQC, HMBC, 1H-1H-COSY) dan MS, bersama dengan pembanding data spektra yang dilaporkan sebelumnya. Senyawa Piloin telah dievaluasi aktivitas antiplasmodiumnya terhadap P. falciparum dengan nilai IC50 sebesar 0.16 ?g/mL.
Pilloin (5,3′-dihidroxy-7,4′-dimetoxy flavon) compound was isolated from stem bark of D. beccariana. The chemical structure of pilloin were determined by spectroscopic data including UV, IR, NMR (1H, 13C, DEPT 135°, HMQC, HMBC, 1H-1H-COSY) and MS, along with by comparison with previosly reported spectra data. Pilloin compound were evaluated their antiplasmodial effect against P. falciparum with IC50 values of 0.16 ?g/mL.