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Total lymphocyte count is a reliable surrogate marker for CD4 cell counts after the first year of antiretroviral therapy: data from an Indonesian cohort study

JudulTotal lymphocyte count is a reliable surrogate marker for CD4 cell counts after the first year of antiretroviral therapy: data from an Indonesian cohort study
PenulisMarrigje A. de Jong, Rudi Wisaksana , Hinta Meijerink, Agnes Indrati , Andre J. A. M. van de Ven , Bachti Alisjahbana , Reinout van Crevel
PenerbitUniversitas Padjadjaran, Tropical Medicine and International Health volume 00 no 00, 2012 Blackwell Publishing Ltd , doi:10.1111/j.1365-3156.2012.02961.x
BahasaBahasa Inggris
Hak CiptaUniversitas Padjadjaran, Tropical Medicine and International Health volume 00 no 00, 2012 Blackwell Publishing Ltd , doi:10.1111/j.1365-3156.2012.02961.x
Kata KunciAntiretroviral therapy, CD4 lymphocyte count, immunological failure, Pneumocystis jirovecii pneumonia-prophylaxis, total lymphocyte count

Many studies have evaluated the total lymphocyte count (TLC) as a cheap surrogate marker for CD4 cells in HIV-infected patients not receiving antiretroviral therapy (ART). We assessed whether TLC can replace CD4 cell counts in evaluating the immunological response to ART. In a cohort of patients in Indonesia TLC, if measured after at least 1-year ART, correctly identi?ed patients with <200 CD4 cells, and reliably excluded immunological failure, obviating the need for CD4 cell measurement in 43% of patients.

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