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Limonoids From The Seeds Of Chisocheton Macrophyllus
Limonoids From The Seeds Of Chisocheton Macrophyllus
Nurlelasari, Dewa Gede Katja, Desi Harneti, Moelyono Moekti Wardayo, Unang Supratman, Khalijah Awang
Universitas Padjadjaran, Chemistry of Natural Compounds, Vol. 53, No. 1, January, 2017, DOI 10.1007/s10600-017-1916-4
Bahasa Inggris
Universitas Padjadjaran, Chemistry of Natural Compounds, Vol. 53, No. 1, January, 2017, DOI 10.1007/s10600-017-1916-4
Chisocheton macrophyllus, dysobinol, limonoid, P-388 murine leukemia cells
Nurlelasari, Dewa Gede Katja, Desi Harneti, Moelyono Moekti Wardayo, Unang Supratman, Khalijah Awang
Universitas Padjadjaran, Chemistry of Natural Compounds, Vol. 53, No. 1, January, 2017, DOI 10.1007/s10600-017-1916-4
Bahasa Inggris
Universitas Padjadjaran, Chemistry of Natural Compounds, Vol. 53, No. 1, January, 2017, DOI 10.1007/s10600-017-1916-4
Chisocheton macrophyllus, dysobinol, limonoid, P-388 murine leukemia cells
A new limonoid compound, dysobinol (1), along with three known limonoid compounds, 7-hydroxyneotricilenone (2), dysobinin (3), and nimonol (4), was isolated from the seeds of Chisocheton macrophyllus (Meliaceae). Their structures were established by spectroscopic techniques such as UV, IR, MS, 1D, and 2D NMR. Compounds 1–4 showed cytotoxic activity against P-388 murine leukemia cells with IC 50 values of 49.7, 79.4, 19.5, and 64.5 g/mL, respectively.
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