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Uji Klinis Chlorhexidine Gloconate 0,2% Dan Povidone Iodine 3% Terhadap Penurunan Hitung Koloni Bakteri Di Pin Site Fiksasi Eksterna Pada Penderita Patah Tulang Terbuka Tibia Derajat III A-B

Uji Klinis Chlorhexidine Gloconate 0,2% Dan Povidone Iodine 3% Terhadap Penurunan Hitung Koloni Bakteri Di Pin Site Fiksasi Eksterna Pada Penderita Patah Tulang Terbuka Tibia Derajat III A-B
Mulyadi D, Rahim HA, Hidajat N, Rasyid NH, Sudigdoadi S
Unpad, Majalah Orthopaedi Indonesia December 2010 Volume XXXVIII No. 2 pp 1-9
Indonesia
Unpad, Majalah Orthopaedi Indonesia December 2010 Volume XXXVIII No. 2 pp 1-9
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Pin site infection is the most common complication for grade III open tibial fracture that is treated with external fixation. There is no standard protocol for pin site care and Hasan Sadikin Hospital Bandung use povidone iodine. Various methods to prevent pin site infection have been proposed; one of them is using antiseptic for the weekly care of pin site. The aim of clinical study is to compare the effectivity of pin site infection prevention by povidone iodine 3% with chlorhexidinegluconate 0,2%, which that has been reported to be the better antiseptic for pin site care. This clinical study consists of 30 subjects that fulfill the inclusion criterias distributed randomly in two treatment groups (chlorhexidine gluconate 0,2%, n=15) and control group (povidone iodine 3%, n=15). As indicated time periode 7th and 14th days swab specimen were taken from pin site area with Levine modification technique, then colony bacterial counting were performed. There were significance differences between pin site care using chlorhexidine gluconate 0,2% and using povidone iodine3% in decreasing the number of bacterial colony count in the 7th and 14th days (p = 0,007 and p =0,002). There is no differences in decreasing of bacterial colony count upon stratification based on open fracture grading ( p=0,694, p=1,0, p=0,942)( p=0,734, p=0,593, p=0,524, p=0,228). Chlorhexidine gluconate 0,2% is more superior in decreasing the number of bacterial colony count at pin sites of an external fixation than povidone iodine 3%.

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