Pustaka Ilmiah Universitas Padjadjaran

Abstrak

Effect of Garlic (Allium sativum) Supplementation on Leukocytes, Neutrophils and Lymphocytes Profile in Quail

Garlic (Alliwn sativum) contains the bioactive component which is diallyl sulphide in the form of oxidized allicin which has the function to stimulate immune system (immunomodulator). Moreover, garlic bas some components namely, alkaIoids, saponin and tannin. Those components have a role as an antibacterial that can increase the number of leukocytes, neutrophils and lymphocytes. The aim of this research was to determine the effect of garlic supplementation on leukocytes, neutrophils and lymphocytes profiles in quail (Coturnix coturnix joponica). This research used 60 quails, age 6 weeks. The method of research using Completely Randomized Design with 4 treatments and repeated 5 times. The treatments are garlic supplementation 0 g(P0), 0.7 g (P1), 1.4 g (P2) and 2.1 g (P3). After 30 days, the total number of leukocytes, neutrophils and lymphocytes was analyzed. The total number of leukocytes, neutrophils, and lymphocytes in quail blood increases because allicin contained in garlic stimulates some interleukins that can increase proliferation. maturation, and kemotaksis. The results showed that garlic supplementation containing 0.7 g, 1.4 g and 2.1 g can increase the number of leukocytes and neutrophils but have no effect on the number of lymphocytes The hignest number. of leukocytes is suplemented garlic 0.7 g, and for neutrophils. is 2,1 g.