Pustaka Ilmiah Universitas Padjadjaran

Abstrak

Diterpenoid compund from leaf of suren (Toona sureni) and yheir toxicity againts brine shrimp

Indonesia is second country with the biggest of biological variety in the world. These natural resources are the main source to get some secondary metabolism compounds which theirs utility have been known specially in health and agricultural fields. Besides of theirs utility, the variety of theirs structures also become an interesting matter for the researchers to keep doing isolation and elucidation of secondary metabolism compounds. Toona sureni is one of potential plant to find some secondary metabolism compounds. This plant which include to family of Meliaceae, was known its activity as insectiside, repellent, antiplasmodial, and antidiarhoea. Through of extraction and isolation method, with so many technic of chromatography, had been got a compound of 3,7,11,15-tetramethyl-2-hexadeken-1-ol (phytol) that include of acyclic diterpene from n-hexane extract of T. sureni leaves. Determinig of its structure was done by spectroscopy method, Infrared (IR) and Nuclear Magnetic Resonance (NMR). Toxicity assay of Brine Shrimp Lethality Test (BSLT) used larvae of Artemia salina as bioindicator showed that phytol was include to good toxic compound with the LC50 value is 16.64 ppm.