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Potential Of Green Leaves Cincau (Premna oblongifolia, Merr) From Indonesia As Anti Cancer

Potential Of Green Leaves Cincau (Premna oblongifolia, Merr) From Indonesia As Anti Cancer
Emma Rochima, Fransiska R. Zakaria, Maggy T. Suhartono, Nurjati C.Siregar
Universitas Padjadjaran, Sustainable Future for Human Security (SustaiN’2010) 11-12 December 2010, Kyoto, Japan

Universitas Padjadjaran, Sustainable Future for Human Security (SustaiN’2010) 11-12 December 2010, Kyoto, Japan
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The aim of the review were to introduce the Green Leaves Cincau Premna oblongifolia Merr from Indonesia which potential as anti cancer. The content of green leaves cincau fiber of 29.37%, the alkaloids of 0.98% and 2.12% total phenols. This compound is thought to provide a pharmacological effect. The alkaloids in the root bisbenzylisoquinoline have cytotoxic activity, chemoprotective potential and act as an antioxidant because it can inhibit lipid peroxides in nonenzimatik. The leaves extract of green jelly is as immunostimulant at low concentration stimulate cell proliferation of lymphocytes in vitro. Also reported that leaves extracts of green jelly has a cytotoxic effect on K-562 cancer cells and hela cervix cancer cell in vitro, and can inhibit proliferation of K-562 cancer cells between 61-95% and hela cervix cancer in 31%.

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