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GRINSPAN’S SYNDROME : A CASE OF THE TRIAD OF ORAL LICHEN PLANUS, HYPERTENSION, AND DIABETES MELLITUS

GRINSPAN’S SYNDROME : A CASE OF THE TRIAD OF ORAL LICHEN PLANUS, HYPERTENSION, AND DIABETES MELLITUS
Irna Sufiawati, Tenny Setiani Dewi
Prosiding Asian Oral Health Care (AOHC) and 2nd ASEAN meeting on Dental Public Helalth (AMDPH), Percetakan Sono Offset
Inggris
Irna Sufiawati, Tenny Setiani Dewi, Asian Oral Health Care (AOHC) and 2nd ASEAN meeting on Dental Public Helalth (AMDPH)
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The triad of oral lichen planus, hypertension and diabetes mellitus has been described before and is known as Grinspan’s syndrome. Drug therapy for diabetes mellitus and hypertension is capable of producing lichenoid reactions of the oral mucosa. We reported a case of a 73-year old womansuffering from oral erosive lesion who received antidiabetic and antihypertensive agents. Topical steroids, antiseptic mouth rinse, and supportive multivitamin were prescribed. She was advised to modify her diet and was also referred to her physician who changes her medication. Her condition improved slightly and he is still under follow up. It appears that proper identification of the causative drug together with its immediate withdrawal and adjunctive topical therapy is an effective method for treating drug-induced lichenoid reactions in this case. It’s concluded that based on clinical features and medical history, the patient was diagnosed Grinspan’s syndrome, and the ultimate confirmation of oral lichenoid reaction is resolution of the condition following withdrawal of the drugs. By taking an active role in the diagnosis and treatment of oral conditions asscociation with systemic disease, dentist may contribute to the maintenance of optimum health.