Abstrak 
Therapeutic Response Evaluation On Hyperthyroidism Using A Fixed Dosed Of I-131
Yulia Kurniawati, AHS Kartamihardja
Universitas Padjadjaran, Poster Presentation 4th International Conference on Radiopharmaceutical Therapy New World Hotel, Ho Chi Minh City, Vietnam 28 Nov – 2 Dec 2011
Bahasa Inggris
Universitas Padjadjaran, Poster Presentation 4th International Conference on Radiopharmaceutical Therapy New World Hotel, Ho Chi Minh City, Vietnam 28 Nov – 2 Dec 2011
hyperthyroidism., I-131
Introduction.Euthyroidism condition is the ideal expected after treatment of hyperthyroidism, but there is still no established therapeutical method that can achieve that condition. Radioactive iodine-131 (131I) has been used to treat hyperthyroidism for long time. It is clinically effective, safe, and cost-effective. However, controversy over the optimum dose of I-131 therapy is still debatable. The aim of this study was to evaluate the therapeutic response of a fixed dosed I-131 in hyperthyroidism patients. Material and method. Retrospective study was carried out during January 2010 until January of 2011. The inclusion criteria were all subjects received I-131 for the first time with a fixed dose of 8 mCi, diffused and high uptake of Tc-99m. Theraupeutical response was evaluated based on the patient’s clinical state and or their laboratory finding3 months after the treatment. Theurapeutical response categorizedgood response if thyroid hormones within normal limit and/or improvement of clinical state, when thyroid hormones still high (above normal value ) with improvement of clinical state was considered as partial response, no respons if there was no changes both on laboratory finding and clinical state. Results. There were 127 patients receiving a fixed dose I-131 therapy of 8 mCi during January 2010 to January 2011. Forty patients did not show a routine examination on third month.The patients were between 12 to 63 years of age. From the 87 patients, 32(36,78%) were no response, still considered in a hyperthyroid condition, 55 (63.21%) patients have good responses, which were20 (36.36%) were hypothyroid, 21 (38.18%) were euthyroid and 14 (25.45%) were partial responses. Conclusion.Fixed dose I-131 therapyof 8 mCi showed good response in our hospital on hyperthyroidism, thereforewe can considered as dose of treatment.