Abstrak 
Hepatic Cirrhosis Due To Asymptomatic Cytomegalovirus Infection In Children
Anthony Sudjadi, Yudith Setiati Ermaya, Dwi Prasetyo
Universitas Padjadjaran, Presentasi Poster Nasional Pertemuan Ilmiah Tahunan Ilmu Kesehatan Anak ke -7 Ikatan Dokter Anak Indonesia Hepatic Cirrhosis Due To Asymptomatic Cytomegalovirus Infection In Children Surabaya 31 Oktober - 4 November 2015
Bahasa Inggris
Universitas Padjadjaran, Presentasi Poster Nasional Pertemuan Ilmiah Tahunan Ilmu Kesehatan Anak ke -7 Ikatan Dokter Anak Indonesia Hepatic Cirrhosis Due To Asymptomatic Cytomegalovirus Infection In Children Surabaya 31 Oktober - 4 November 2015
Hepatic cirrhosis
Background : Hepatic cirrhosis is defined as a diffuse process, characterized by fibrosis and nodular regeneration, causing liver architecture’s disorganization. Hepatic cirrhosis usually caused by chronic viral hepatitis, including CMV infection, which prevalence nearly 1% of all newborns, and could be reactivated or reinfected at any age. Objective : To report an unusual manifestations of hepatic cirrhosis due to CMV infection. Case Illustration : A 13 year old girl Chief complaint: hematemesis Has been diagnosed hepatic cirrhosis caused by CMV infection last year. No history of blood transfusion, organ transplantation, or consumption of immunosuppressive drugs. Physical examination: Pallor, jaundice, and ascites. Laboratory findings: a. Pancytopenia, b.Prolonged coagulation time c. decreased protein serum d. Reactive IgM and IgG anti-CMV e. Last year: reactive IgG anti CMV, non reactive IgM anti CMV f. Non reactive HIV antibody. Ultrasonography: g. Hepatic cirrhosis pattern. Endoscopy: h. Esophageal varices grade 1 i. Moderate to severe portal hypertension gastropathy. Follow up during hospitalization: Persistent coagulation derangements and thrombocytopenia. Diagnosis: hepatic cirrhosis caused by CMV infection with slight pleural effusion Treatment: symptomatically: fresh frozen plasma transfusion, UDCA, propranoiol, spironolactone, and antibiotic intravenously. We conclude this patient had a poor outcome. Conclusion : Hepatic cirrhosis can be a complication from CMV infection in children but unusually happens in children with asymptomatic presentation at early years of life. We need to detect CMV infection in early days of life and detect it’s reactivation and reinfection