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ATTEMPTED PREPARATION OF FMOC-(S)-Β-HYDROXYMETHYLVALINE

ATTEMPTED PREPARATION OF FMOC-(S)-Β-HYDROXYMETHYLVALINE
Rani Maharani
Jurnal Chimica et Natura Acta (CNA) Jurusan Kimia FMIPA Unpad
Inggris
Rani Maharani, Jurnal Chimica et Natura Acta (CNA) Jurusan Kimia FMIPA Unpad
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Abstract: Fmoc-(R)-β-hydroxyvaline was successfuly synthesised as an undesired product through a diastereoselective aldol condensation. However, the desired product was unsuccessfully produced. The undesired Fmoc-(R)-β-hydroxyvaline was then trialed for the oxazolidinone formation. Unfortunately, the oxazolidinone of the amino acid was not obtained. It was suggested that the hydroxyl group protection of the amino acid was needed.

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