Abstrak 
Reply to “Strategy To Limit Sampling of Antituberculosis Drugs Instead of Determining Concentrations at Two Hours Postingestion in Relation to Treatment Response”
Reply to “Strategy To Limit Sampling of Antituberculosis Drugs Instead of Determining Concentrations at Two Hours Postingestion in Relation to Treatment Response”
Rob Aarnoutse, Carolien Ruesen, Erlina Burhan, Reinout van Crevel, Rovina Ruslami
Universitas Padjadjaran, Antimicrobial Agents and Chemotherapy January 2014 Volume 58 Number 1 doi:10.1128/AAC.01651-13
Bahasa Inggris
Universitas Padjadjaran, Antimicrobial Agents and Chemotherapy January 2014 Volume 58 Number 1 doi:10.1128/AAC.01651-13
antituberculosis (anti-TB
Rob Aarnoutse, Carolien Ruesen, Erlina Burhan, Reinout van Crevel, Rovina Ruslami
Universitas Padjadjaran, Antimicrobial Agents and Chemotherapy January 2014 Volume 58 Number 1 doi:10.1128/AAC.01651-13
Bahasa Inggris
Universitas Padjadjaran, Antimicrobial Agents and Chemotherapy January 2014 Volume 58 Number 1 doi:10.1128/AAC.01651-13
antituberculosis (anti-TB
As the number of studies examining the relationship between plasma concentrations of antituberculosis (anti-TB) drugs and treatment response is limited, our Indonesian-Dutch team performed a practical field pharmacokinetic study recently published in this journal (1). Despite large interindividual variability in plasma concentrations of TB drugs at 2 h postdose (C2 h) no associations were found between isoniazid, rifampin, and pyrazi-namide C2 h values and sputum culture results after 8 weeks of TB treatment. These results contrast with findings in several (2–6) but not all (7,8) similar studies.
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