Abstrak 
Activity of Flavonoid and Antraquinone Derivatives from Cassia sp. as an Antifungal Treatment for Skin Disease
Tiana Milanda, Yasmiwar Susilawati, Anis Yohana Chaerunisaa
Universitas Padjadjaran, International Seminar dan Expo On Jamu 2010
Bahasa Inggris
Universitas Padjadjaran, International Seminar dan Expo On Jamu 2010
' Cassia fistula, antifungal activity, Cassia javanic, Cassia torosa, Mycosporum gypseum
Topical disease caused by fungal infection (dermatophytosis) is important problem in Indonesia, which has tropical climate and relatively high humidity. Some traditional plants had been used in the treatment of skin diseases caused by fungal infection are Cassia sp. The aim of the research was to study bioactive antifungal compound from Cassia sp. against pathogenic skin fungi. The result showed that Minimum Inhibitory Concentration (MIC) of methanol extract and ethyl asetate (EA) fraction from Cassia fistula and Cassia javanica were 600 ppm against Mycosporum gypseum, while Cassia torosa extract did not gave the antifungal activity. Isolation and purification process showed that antifungal bioactive compound from ethyl acetat fractions (EA1.2.2 and EA2.3.1 fractions) were white needle crystalline. Based on phytochemistry screening, Thin Layer Chromatography results, UV and IR spectra datas, it can be concluded that biaoctive compound from these fractions which had antifungal activity are flavonoid compound.