Abstrak 
Antihypertensiveactivity Of “Rovela”: Combination Of Roselle Flowers(Hibiscus Sabdariffa L.), Chayotefruits(Sechiumedu/E(Jacq.) Sw.), Andaloe Vera Leaves (Aloe Vera(L.)Burm.F.) Extracts
Dr. Ahmad Muhtadi, Tiana Milanda,Yasmiwar Susilawati, Sriwidodo, Bella Puspa W.
Universitas Padjadjaran, Seminar International Seminar On Pharmaceutical Science On Technology
Bahasa Inggris
Universitas Padjadjaran, Seminar International Seminar On Pharmaceutical Science On Technology
Aloe vera, antihypertensive, Non-Invasive Blood Pressure Volume Pressure Recording, Roselle, Sechium edule
According to the WHO in 2011, 8 million people in the world each year died because of hypertension, whereas the prevalence in Indonesia was quite high at 29.8% in 2007. Various herbs can be used as an alternative for treat hypertension because it is safer and relatively had no side effect. We examined the antihypertensive activity from 4 combination doses of roselle flowers, chayote fruits, and aloe vera leaves. The antihypertensive activity was tested on white male rats Sprague-dawley strain induced adrenaline 1.2 pg/kgintraperitoneally with Non¬invasive Blood Pressure Volume Pressure Recording methods. The results showed that the activity of systole and diastole blood pressure dose 1, dose 3 and dose 4 has a significant difference to the negative control, and did not have a significant difference to the positive control. Dose of antihypertensive activity that had the best activity was dose 3 with an average percentage activity in decrease systole and diastole blood pressure respectively by 18.31% and 23.19%.