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New Bisamide Compounds From The Bark Of Aglaia Eximia (Meliaceae)

New Bisamide Compounds From The Bark Of Aglaia Eximia (Meliaceae)
Julinton Sianturi, Mayshah Purnamasari, Darwati, Desi Harneti, Tri Mayanti, Unang Supratman, Khalijah Awang, Hideo Hayashi
Universitas Padjadjaran, Phytochemistry Letters 13 (2015) 297-301, Contents lists available at ScienceDirect, journal home page : www.elsevier.com/locate/phytol
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Universitas Padjadjaran, Phytochemistry Letters 13 (2015) 297-301, Contents lists available at ScienceDirect, journal home page : www.elsevier.com/locate/phytol
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Two new bisamide compounds, eximiamide A (1) and eximiamide B (2) were isolated from the bark of Aglaia eximia (Meliaceae). The chemical structures of the new compound were elucidated on the basis of spectroscopic data. All of the compounds were evaluated for their cytotoxic effects against P-388 murineleukemia cells. Compounds 1 and 2 exhibited cytotoxic activity against P-388 murine leukemia cells with IC50 of values of 7.6 and 8.5 ug/mL, respectively.

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