Pustaka Ilmiah Universitas Padjadjaran

Abstrak

A Multicenter Surveillance and Reporting of Antimicrobial Resistance: Focus on Ceftriaxone-Resistant Escherichia coil in the Year 2012 and 2013

Introduction: Bacterial resistance to commonly prescribed antibiotics is increasing both in developing and developed countries. Resistance to more potent antimicrobial agents has also emerged. The present study aims to report information concerning Escherichia coli resistance to cefiriaxone from clinical specimens from three hospitals in Bandung, Indonesia. Method: A total of 234 specimens in 2012 and 601 specimens in 2013 were collected from all three hospitals. The results were processed to obtain the profile prevalence ceftriaxone-resistant E. coil and the distribution on infected specimens. Result: Increasing number of ceftriaxone-resistant E. Coil were observed in two hospitals, hospital A from 35.38% to 43.02% and hospital C from 43.9% to 52.6%. The source of clinical specimen of E. coli resistant to ceftriaxone was varied in all hospital. In hospital A, pus and faeces were the predominant infected specimens. Meanwhile in hospital B, sputum was the predominant infected specimen, and in hospital C urine was the most common specimen infected by ceftriaxoneresistant E. coil. Conclusion: The high and increasing rate of ceftriaxone- resistant E. Coil indicate that it is imperative to rationalize the use of antimicrobials in hospitals, use them prudently and also mandate our attention, and periodic monitoring of the trend of the resistance is crucial. A team-based approach to patient care is needed between pharmacist and prescriber to combat antibiotic resistance.