Abstrak 
Activity Of Cassia Fistula L. Barks Fractions As Antibacterial Agent
Anis Yohana Chaerunisaa, Tiana Milanda, Yasmiwar Susilawati
Universitas Padjadjaran, Journal Of Pharmaceutical Sciences And Research Vol. 10(2), 2018, 304-309, ISSN : 0975-1459, www.jprs.pharmainfo.in
Bahasa Inggris
Universitas Padjadjaran, Journal Of Pharmaceutical Sciences And Research Vol. 10(2), 2018, 304-309, ISSN : 0975-1459, www.jprs.pharmainfo.in
' Cassia fistula, antimicrobe, fractions
Cassia fistula L. has been used as alternative medicine indicated to have various efficacies. Some studies proved that some parts of this plant have antibacterial and antifungal activity, but activity from the barks of this plant has not been styudied yet. In this study, the sample were extracted by Ethanol, continued by fractination by n-hexane, ethyl acetate and water. Phytochemical screening were performed by methods explained by Fansworth. Antibacterial study of the extract were conducted by diffusion agar method against Escherichia coli and Staphylococcus aureus. The result showed that Minimum Inhibitory Concentration of ethyl acetate fraction was at 0,625 % agaianst S. aureus while water fraction was more than 10%. MIC against E. coli of water fraction was more than 10% and ethyl acetate fraction was at 1,25%. Antibacterial activity study was perfomed by difusion method and was compared to that of amoxicillin as marketed oral antibiotic. The results showed that ethyl acetate fraction showed strongest activity ainst both S. aureus and E. Coli. The study concluded that pontential antimicrobial properties of ethyl acetate fraction of Cassia fistula ethyl illustrates the promising activity in exploring new antibacterial agent.