Abstrak 
Flavonoids Compounds from the Leaves of Kalanchoe prolifera and Their Cytotoxic Activity against P-388 Murine Leukimia Cells
Flavonoids Compounds from the Leaves of Kalanchoe prolifera and Their Cytotoxic Activity against P-388 Murine Leukimia Cells
Lilis Siti Aisyah, Yenny Febriani Yun, Tati Herlina, Euis Julaeha, Achmad Zaenuddin, Ida Nurfarida ,Ace Tatang Hidayat, Unang Supratman,, Yoshihito Shiono
Universitas Padjadjaran, Natural Product Sciences 23(2) : 1-7 (2017), https://doi.org/10.20307/nps.2017.23.2.1
Bahasa Inggris
Universitas Padjadjaran, Natural Product Sciences 23(2) : 1-7 (2017), https://doi.org/10.20307/nps.2017.23.2.1
Crassulaceae, Flavonoids, Kalanchoe prolifera, P-388 murine leukimia cell
Lilis Siti Aisyah, Yenny Febriani Yun, Tati Herlina, Euis Julaeha, Achmad Zaenuddin, Ida Nurfarida ,Ace Tatang Hidayat, Unang Supratman,, Yoshihito Shiono
Universitas Padjadjaran, Natural Product Sciences 23(2) : 1-7 (2017), https://doi.org/10.20307/nps.2017.23.2.1
Bahasa Inggris
Universitas Padjadjaran, Natural Product Sciences 23(2) : 1-7 (2017), https://doi.org/10.20307/nps.2017.23.2.1
Crassulaceae, Flavonoids, Kalanchoe prolifera, P-388 murine leukimia cell
Seven flavonoid compounds, kaempferol (1), quercetin (2), quercetin-3-O-ß-D-glucopyranoside (3), kaempferol-3-O-ß-D-glucopyranoside (4), kaempferol-3-O-a-L-rhamnoside (5), quercetin-3-O-sophoroside (6) and quercetin-3-O-rutinoside (7), were isolated from the methanolic extract of leaves of Kalanchoe prolifera. Compounds 1-7 were isolated for first time from this plant. These compounds were evaluated their cytotoxic activity against P-388 murine leukimia cells in vitro. Among those compounds kaempferol (1) and quercetin (2) showed strongest cytotoxic activity with IC50 values of 4.45 ± 0.05 and 6.28 ± 0.02 µg/mL, respectively.
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