Abstrak 
Ant Nest Plant Ethanol Extract (Myrmecodia Pendens Merr. And L.M Perry) Against Microsporum Gypseum As Antidermatophyte Natural Agent
Sulistiyaningsih Sulistiyaningsih, Ayu Shofi Cholifati, Sri Agung Fitri Kusuma
Universitas Padjadjaran, Journal of Pharmacy Research Vol 12 Issue 4 2018, ISSN: 0974-6943, Website: jprsolutions.info
Bahasa Inggris
Universitas Padjadjaran, Journal of Pharmacy Research Vol 12 Issue 4 2018, ISSN: 0974-6943, Website: jprsolutions.info
Antidermatophite, microsporum gypseum, Myrmecodia pendens
Aim: The aim of this study is to evaluate the in vitro antidermatophyte activity of ethanol extracts from ant nest plant against Microsporum gypseum. Methods: In this experimental study, the ant nest plants were taken and extractions were made in ethanol and were tested against M. gypseum. The screening of secondary metabolite in the extract was done using standard methods. The antifungal activity of the extract was conducted using the agar diffusion method. The minimum fungicidal concentration (MFC) was determined using the broth macrodilution method. Result and Discussion: The secondary metabolites screening of ant nest plant ethanol extract revealed the presence of polyphenols, flavonoids, tannins, and saponins. The extract under review showed antifungal activity against M. gypseum with MFC values ranging from 1.5% to 1.7% w/v using the broth dilution method. Conclusion: The ant nest plants have pharmacological value as a natural product, and it is necessary for further investigation as a potential useful agent for the treatment of dermatophytosis.