Pustaka Ilmiah Universitas Padjadjaran

Abstrak

The Excretion Profiles Of Vitamin C From Vitamin C And Ester-c Tablets In Human Urine

Purpose: The purpose of this research is to study the excretion profile of vitamin C in urine. Methods: Urine samples from six volunteeres were collected in the interval of 0, 2, 4, 8, 10, 15, 20, and 24 hours after the volunteers have been given vitamin C and Ester-C® tablets, orally. The method o f analysis used was visible spectrophotometry (UV/Visible Ultrospec 3000 pro) with dichlorophenol indophenol as the reagent. Result: Result showed that the total percentage of vitamin C in urine after admin istration of vitamin C tablet was 9.44% (of 240.64 mg dosage ), with the highest concentration of excretion was at the 6th hour. The total percentage of vitamin C in urine after administration of Ester-C® tablet was 1.30% (of 236.925 m g dosage), with the highest co ncentration of excretion was a t the 15th hour. The accuracy and precision of this method were proven fulfilled the criteria of validation.