Abstrak 
Antimutagenic Activity Of Sintoc Bark (Cinnamomum sintoc Bl.) Volatile Oil With Micronucleus Method
Sri Adi Sumiwi, Tiana Milanda, Fazri Prakarsa
ISC-2011 (the 2nd International Seminar on Chemistry 2011)
Inggris
ISC-2011 (the 2nd International Seminar on Chemistry 2011), Sri Adi Sumiwi, Tiana Milanda, Fazri Prakarsa
Antimutagenic, Cinnamomum sintoc Bl
Sintoc bark (Cinnamomum sintoc Bl.) has many benefits, one of the efficacious compounds from these plants is volatile oil. Sintoc bark volatile oil are known to have antioxidant activity, antimutagenic test is carried out on rats using micronucleus method. The test materials were administered orally at a dose of 0.01 mL/200g, 0.025 mL/200 g, and 0.05 mL/200g. Antimutagenic effect evidenced by a decreasing number of micronucleus polychromatic erythrocytes per 1000 cells in preparations of bone smears.The results showed that volatile oil at all dose tested could reduce the number of micronucleus. Volatile oil dose 0.01 mL/200g decreased by 46.03%, 0.025 mL/200g dose of 38.73%, and a dose of 0.05 mL/200g of 29.21%. The final conclusion sintoc bark volatile oil a dose of 0.01 mL/200g antimutagenic effect best with the greatest reduction in micronucleus.